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Fig. 11 | BMC Pharmacology and Toxicology

Fig. 11

From: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice

Fig. 11

Clinical appearance of right hind paws. (a) Radiographic evidence of right hind paw from (1) Vehicle control, (2) negative control group, (3) positive control group and (4) poncirin treated group. Tissue swelling can be observed in the tibiotarsal region of CFA treated mice as compared to poncirin treated mice. (b) Histopathological analysis of tibiotarsal joint from (1) vehicle control, (2) negative control group, (3) positive control treated group and (4) poncirin treated group. Paw tissues were sectioned at 4 μm thickness, stained by hematoxylin-eosin and observed with the microscope (40×). Note marked immune cell infiltration, synovial hyperplasia, in the vehicle-treated group as compared to poncirin treated group

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