Fig. 2

Inhibition of formalin-induced paw licking and total time spent in paw licking was reduced by poncirin. The total time spent in paw licking was observed for 0–10 min (a) and 10–30 min (b) after formalin injection. Treatment with piroxicam (5 mg/kg, i.p) was used as a control. Each column represents the mean ± SEM of 6–7 mice per group. *p < 0.05, **p < 0.01 and ***p < 0.001 denote the significant differences from the negative control group