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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes

Fig. 4

Knockdown of HIF-1α attenuated Ang II-induced inflammatory cytokine production in podocytes. a Podocytes were transfected with siRNA 934, 1067 or 1217 to knock down HIF-1α expression. Untreated and scramble siRNA transfected podocytes (scramble negative control, SNC) were designated as the normal group. β-Tubulin was used as an equal loading marker. (*p < 0.05 in one-way ANOVA, n = 3). b Podocytes were transfected with siRNA 934 and then stimulated with 10-7 M Ang II for 12 h. β-Tubulin was used as an equal loading marker. (*p < 0.05 in one-way ANOVA, n = 3). c Podocytes were transfected with siRNA 934 and then stimulated with 10-7 M Ang II for 12 h. Representative Western blots of MCP-1 and TNF-α expression in the different groups. β-Tubulin was used as an equal loading marker. (*p < 0.05 in one-way ANOVA, n = 3)

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