Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants

Table 5 Multiple linear regression models

	IL-1β (pg mL^− 1)		IL-6 (pg mL^− 1)		TNF-α (pg mL^− 1)		INF-γ (pg mL^− 1)
	R square = 0.579		R square = 0.555		R square = 0.584		R square = 0.627
	Β	p-values	β	p-values	β	p-values	β	p-values
Benzene (μg m⁻³)^a	0.437	p < 0.05	0.519	p < 0.05	0.496	p < 0.05	0.388	p < 0.05
Toluene (μg m⁻³)^a	0.213	p > 0.05	0.270	p > 0.05	0.221	p > 0.05	0.268	p > 0.05
m-Xylene (μg m⁻³)^a	− 0.250	p > 0.05	− 0.182	p > 0.05	− 0.333	p > 0.05	− 0.080	p > 0.05
p-Xylene (μg m^− 3)^a	− 0.259	p > 0.05	− 0.285	p > 0.05	− 0.349	p > 0.05	− 0.177	p > 0.05
t,t-MA (μg g^− 1 creatinine)^a	− 0.319	p > 0.05	− 0.212	p > 0.05	−0.300	p > 0.05	−0.058	p > 0.05
CD86 monocyte expression (%)^a	−0.404	p > 0.05	−0.381	p > 0.05	−0.428	p > 0.05	−0.374	p > 0.05
PCO (nmol mg⁻¹ protein)^a	0.140	p > 0.05	0.017	p > 0.05	0.051	p > 0.05	0.053	p > 0.05
GST (U GST mg⁻¹ protein)^a	−0.165	p > 0.05	−0.071	p > 0.05	−0.196	p > 0.05	−0.155	p > 0.05
Exposure time (years)^a	−0.463	p > 0.05	−0.481	p > 0.05	−0.461	p > 0.05	−0.387	p > 0.05
Age (years)^a	0.277	p > 0.05	0.229	p > 0.05	0.148	p > 0.05	0.161	p > 0.05
Smoking^b	−0.129	p > 0.05	−0.087	p > 0.05	−0.085	p > 0.05	−0.123	p > 0.05

t,t-MA trans,trans-muconic acid, IL-1β interleukin-1β, IL-6 interleukin-6, TNF-α tumor necrosis factor-α, IFN-γ interferon-γ, PCO protein carbonyl, GST glutathione S-transferase
^aCategorical variable
^bContinuous variable

ISSN: 2050-6511