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Table 1 Comparison of curative effects between patients with different clinical features [n (%)]

From: Application effect of apatinib in patients with failure of standard treatment for advanced malignant tumours

Variable

n

CR

PR

SD

PD

ORR

χ2

P

ECOG

 1

11

0

3(27.3)

6(54.4)

2(18.2)

3(27.3)

  

 2

14

0

2(14.3)

8(57.1)

4(28.6)

2(14.3)

7.731

0.021

  ≥ 3

6

0

0

1(16.7)

5(83.3)

0

  

Sex

 Male

17

0

2(11.8)

10(58.8)

5(29.4)

2(11.8)

0.606

0.436

 Female

14

0

3(21.4)

5(35.7)

6(42.9)

3(21.4)

  

Chemotherapy

 Yes

2

0

1(50.0)

1(50.0)

0

1(50.0)

1.176

0.278

 No

29

0

14(48.3)

14(48.3)

11(37.9)

14(48.3)

  

Treatment lines

 first-line

8

0

3(37.5)

3(37.5)

4(50.0)

3(37.5)

  

 second-line

7

0

5(71.4)

5(71.4)

1(14.3)

5(71.4)

2.139

0.343

 third-line

16

0

7(43.8)

7(43.8)

6(37.5)

7(43.8)

  

metastatic sites

  < 3

17

0

11(64.7)

11(64.7)

3(17.6)

11(64.7)

5.231

0.022

  ≥ 3

14

0

4(28.6)

4(28.6)

8(57.1)

4(28.6)