Fig. 5
From: Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2)
a STX3451 and STX2895 resulted in cytoskeletal structural changes and apoptotic cell death in NF2 tumor cells after 72 h of treatment. Cells were stained with DAPI for nuclei (blue), anti-α-tubulin antibody for microtubules (red), and annexin V for apoptotic cells (green). b Percentage of annexin-V-positive cells for control and treated conditions. DMSO; STX3451; STX2895; PF; Frax1036. Statistical significance: *p < 0.05; **p < 0.01