TY - JOUR AU - Wang, Zhuoying AU - Denys, Ian AU - Chen, Feng AU - Cai, Lijie AU - Wang, Xuecui AU - Kapusta, Daniel R. AU - Lv, Yongliang AU - Gao, Juan PY - 2019 DA - 2019/12/02 TI - Complete atrioventricular block due to timolol eye drops: a case report and literature review JO - BMC Pharmacology and Toxicology SP - 73 VL - 20 IS - 1 AB - Timolol Maleate is a non-selective beta-adrenergic blocker that is commonly used to treat open-angle glaucoma. Despite its topical administration, ophthalmic timolol enters systemic circulation and produces a systemic beta-adrenergic blockade. We report a case of long-term timolol use that uncovered and worsened an underlying cardiac conduction defect demonstrated as a third degree atrioventricular (AV) block. SN - 2050-6511 UR - https://doi.org/10.1186/s40360-019-0370-2 DO - 10.1186/s40360-019-0370-2 ID - Wang2019 ER -