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Fig. 8 | BMC Pharmacology and Toxicology

Fig. 8

From: KEA-1010, a ketamine ester analogue, retains analgesic and sedative potency but is devoid of Psychomimetic effects

Fig. 8

Minimal psychoactivity of KEA-1010 when administered to rats receiving saline or morphine via minipump. Behavioural dysfunction scoring in rats receiving saline and morphine via subcutaneous minipump on days one (a, b) and day six (c, d) following injection of KEA-1010 and ketamine. Data mean (SEM). *P < 0.05, **P < 0.01, ***P < 0.001 (KEA-1010 vs. ketamine; Bonferroni). N = 6 all groups

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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