Molecular Target (Assay Type) | Ketamine | KEA-1010 | KEA-1025 |
---|---|---|---|

IC_{50} [Percent Inhibition at 10 μM] | |||

Ca^{2+} Channel L-Type(Radioligand Binding) | > 10 μM [24%] | > 10 μM [−] | > 10 μM [−] |

GABA_{A} Receptor(Radioligand Binding) | > 10 μM [−] | > 10 μM [−] | > 10 μM [−] |

δ_{1} Opiate Receptor(Radioligand Binding) | > 10 μM [−] | > 10 μM [−] | > 10 μM [−] |

μ Opiate Receptor (Radioligand Binding) | > 10 μM [−] | > 10 μM [−] | > 10 μM [−] |

Norepinephrine Uptake Site (Functional Uptake Assay) | > 10 μM [23%] | > 10 μM [−] | > 10 μM [−] |

HCN1 K^{+} Channel(Patch-Clamp Functional Assay) | > 100 μM [15%] | > 100 μM [20%] | > 100 μM [−] |