Genotype | Crude OR(95%CL) | P value | Adjusted OR (95%CL) | P value |
---|---|---|---|---|
CYP2C19*2(GG) | 1 | Â | 1 | Â |
CYP2C19*2(GA) | 2.81(1.12–6.59) | 0.018 | 2.99(1.11–8.03) | 0.03 |
CYP2C19*2(AA) | 12.47(3.77–41.22) | < 0.001 | 8.62(2.29–32.46) | 0.001 |
CYP2C19*3(GG) | 1 | Â | 1 | Â |
CYP2C19*3(GA) | 5.31(1.96–14.41) | < 0.001 | 3.64(0.98–13.56) | 0.054 |
1*/1* | 1 | Â | 1 | Â |
1*/2* | 4.41(1.35–14.41) | 0.14 | 6.65(1.77–25.04) | 0.005 |
1*/3* | 10.89(2.36–50.30) | 0.002 | 22.74(3.11–166.27) | 0.002 |
2*/2* | 27.96(6.77–115.52) | < 0.001 | 48.49(8.16–287.97) | < 0.001 |
2*/3* | 106.75(10.42–1093.57) | < 0.001 | 241.32(14.59–3991.37) | < 0.001 |
PON1(Q192R)QQ(AA) | 1 | Â | 1 | Â |
PON1(Q192R)QR(AG) | 2.68(0.56–12.90) | 0.22 | 3.01(0.53–17.05) | 0.213 |
PON1(Q192R)RR(GG) | 5.47(1.19–25.23) | 0.029 | 5.69(1.06–30.47) | 0.042 |