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Table 5 Haplotype analysis on association of CYP2C19, PON-1 gene and clopidogrel resistance

From: The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention

Haplotypes

(rs4244285,

rs s4986893)

Frequencies

OR (95% CL)

P-values

Case group

N (%)

Control group

N (%)

AG*

12(0.150)

8(0.033)

5.119(2.01–13.035)

0.000191

GA*

41(0.512)

58(0.242)

3.299(1.944–5.597)

5.8e-006

GG*

27(0.338)

174(0.725)

0.193(0.112–0.333)

5.71e-010

  1. The frequency of haplotype below 0.03 was not included in the table; P-value < 0.05 was defined as the level of significance