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Table 6 Occurrence of adverse cardiovascular events between the different CYP2C19 genotypes and PON-1 Q192R genotypes

From: The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention

group

Genotype

MACE

NON-MACE

P

CYP2C19

*1/*1

2

63

 

*1/*2

18

40

< 0.001

*1/*3

3

9

0.025

*2/*2

11

6

< 0.001

*2/*3

7

1

< 0.001

 

AA(QQ)

3

20

 

PON-1

AG(QR)

13

51

0.534

 

GG(RR)

25

48

0.051

  1. p < 0.05 was considered significant
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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