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Table 3 Indole derivatives with CobA inhibition potential in all pathogens under study

From: Prospects of Indole derivatives as methyl transfer inhibitors: antimicrobial resistance managers

Zinc Ids

Ng

− 6.7*

Ab

− 8.8*

Cc

− 7.9*

Kp

− 8.4*

Ef

Hp

− 7.7*

Pa

− 6.0*

Sa

− 7.4*

St

−8.2*

ZINC04899565

−8.0

−9.5

−8.7

− 9.5

#

− 8.6

− 7.2

−8.4

−9.2

ZINC49171024

−7.3

−9.1

−9.2

− 9.2

#

−8.4

− 6.9

− 8.1

−9.2

  1. *Binding energy of native ligand
  2. # B. E not calculated due to unavailability of valid 3D structure.