Table 4 Baseline values of laboratory parameters
Laboratory parameters | Sitagliptin | Vildagliptin | Teneligliptin | Alogliptin | Linagliptin | p-value |
|---|---|---|---|---|---|---|
mean (95%CI) | mean (95%CI) | mean (95%CI) | mean (95%CI) | mean (95%CI) | ||
HbA1c (%) | 7.8 (7.7, 7.9) | 7.8 (7.6, 7.9) | 7.8 (7.7, 8) | 7.4 (7.2, 7.6) | 7.4 (7.3, 7.6) | <.0001* |
Creatinine (mg/dL) | 0.8 (0.77, 0.82) | 0.89 (0.85, 0.93) | 0.94 (0.9, 0.98) | 0.82 (0.78, 0.87) | 1.04 (0.99, 1.09) | <.0001* |
eGFR (mL/min/1.73m2) | 74 (72.6, 75.5) | 70.3 (67.6, 73.1) | 66.3 (63.7, 68.9) | 72.5 (69.7, 75.3) | 61.8 (58.6, 65) | <.0001* |
HDL (mg/dL) | 51.3 (50.3, 52.3) | 47.3 (45.4, 49.1) | 50.1 (48.3, 52) | 47.5 (45.6, 49.5) | 48.9 (46.7, 51.1) | 0.0002* |
TC (mg/dL) | 192.3 (189.6, 194.9) | 188.7 (183.7, 193.7) | 190.1 (185.2, 194.9) | 188 (182.6, 193.4) | 189.3 (183.5, 195.1) | 0.5242 |
TG (mg/dL) | 145 (139.1, 151) | 160.3 (148.9, 171.7) | 151.3 (140.5, 162) | 155 (143.3, 166.6) | 146.2 (133.2, 159.2) | 0.1483 |
AST (U/L) | 27.8 (26.5, 29.1) | 30.3 (27.9, 32.7) | 29.8 (27.5, 32.2) | 29.9 (27.4, 32.4) | 24.7 (21.9, 27.5) | 0.0124* |
ALT (U/L) | 30.4 (28.7, 32.1) | 32.3 (29.1, 35.6) | 30.2 (27.1, 33.3) | 34.7 (31.4, 38.1) | 26.2 (22.4, 29.9) | 0.0157* |