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Table 1 Reported outcomes to be assessed

From: Dual anti-platelet therapy following percutaneous coronary intervention in a population of patients with thrombocytopenia at baseline: a meta-analysis

Studies

Outcomes which were reported after PCI in the original studies respectively

Follow-up time period after PCI

Types of CAD

Ayoub 2018 [8]

Post-procedural hemorrhage, RBC transfusion, platelet transfusion, vascular complications, acute ischemic CVA, acute hemorrhagic CVA, cardiac tamponade, mortality

In-hospital

General population with CAD + chronic thrombocytopenia undergoing PCI

Ito 2018 [9]

Myocardial infarction, GUSTO moderate bleeding, GUSTO severe bleeding, all-cause death, cardiac death, ischemic stroke, all stroke, hemorrhagic stroke, definite stent thrombosis, definite/probable stent thrombosis, any coronary revascularization, intracranial bleeding, gastrointestinal bleeding, bleeding related to surgery, bleeding related to catheterization procedure

3 years

General population with CAD + thrombocytopenia undergoing PCI

Kiviniemi 2013 [10]

All-cause mortality, MACCE, stroke, peripheral arterial embolism, myocardial infarction, revascularization, stent thrombosis, venous thromboembolism, total bleeding events, minor BARC 2 bleeding, major BARC bleeding (3a, 3b, 3c, 5)

1 year

CAD and atrial fibrillation + thrombocytopenia undergoing PCI

Liu 2018 [11]

All-cause mortality, cardiac death, myocardial infarction, revascularization, bleeding, major bleeding, ischemic stroke, MACE, definite stent thrombosis, definite and probable stent thrombosis, early, late and very late stent thrombosis

30 months

General population with CAD + thrombocytopenia undergoing elective PCI

Overgaard 2008 [12]

Mortality, MACE, myocardial infarction, major bleeding, gastro-intestinal bleed, intracranial hemorrhage, other bleedings, access site complications, transfusion

In-hospital

General population with CAD + thrombocytopenia undergoing PCI

Raphael 2016 [13]

Femoral bleeding, intra-cerebral bleeding, hematoma, gastro-intestinal bleeding, retroperitoneal bleeding, any bleeding, death, myocardial infarction, access site bleeding, BARC 2 minor bleeding, BARC (3a, 3b, 4) major bleeding

In-hospital

General population with CAD + thrombocytopenia undergoing PCI

Shiraishi 2019 [14]

Mortality, transfusion, access site bleeding

In-hospital

General population with CAD + thrombocytopenia undergoing elective PCI

Yadav 2016 [15]

Death, cardiac death, myocardial infarction, revascularization, definite/probable stent thrombosis, MACE

1 year

ACS (STEMI and NSTEMI) + thrombocytopenia undergoing PCI

  1. Abbreviations: PCI percutaneous coronary intervention, CAD coronary artery disease, ACS acute coronary syndrome, CVA cerebrovascular attack, RBC red blood cells, MACCE major adverse cardiac and cerebrovascular events, MACE major adverse cardiac events, BARC bleeding defined according to the academic research consortium