Skip to main content

Table 2 Subgroup analyses of AF exposure and risk of liver cirrhosis using unadjusted ORs

From: Aflatoxins as a risk factor for liver cirrhosis: a systematic review and meta-analysis

Subgroup

Studies, N

OR (95% CI)

p value

Tests for heterogeneity

Q

p

I2

All studies

8

3.35 (2.74,4.10)

0.000

59.58

0.000

88.3%

Study design

 Case-control studies

7

3.67 (2.93,4.59)

0.000

56.38

0.000

89.4%

 Nested case-control studies

1

2.29 (1.44,3.64)

0.000

0.00

–

–

Method of AF exposure assessment

 Serum AF-albumin adduct level

3

4.89 (3.77, 6.35)

0.000

17.83

0.000

88.8%

 249ser TP53mutation

3

4.3 (2.55,7.26)

0.000

0.30

0.863

0.0%

 Groundnut consumption

2

1.15 (0.76,1.72)

0.51

5.68

0.017

82.4%

Geographic location

 Asia

4

4.85 (3.75,6.26)

0.000

18.01

0.000

83.3%

 Africa

4

1.84 (1.32,2.55)

0.000

20.75

0.000

85.5%

  1. AF Aflatoxin, OR Odds ratio, CI Confidence interval