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Table 4 Relevant clinical manifestations and diagnostic basis of bone tumor, myeloma and adverse drug reactions for this patient

From: Osteomalacia and renal failure due to Fanconi syndrome caused by long-term low-dose Adefovir Dipivoxil: a case report

Diagnostic Criteria

Bone tumor

Myeloma

Adverse Drug Reactions

Patient’s condition

Pain, swelling or mass

+

+

+

+

Systemic symptoms

 (anemia, progressive emaciation, insomnia, irritability, ect

+

+

+

+

 hepatomegaly

+

 renal failure

+

+

+

 Lymphadenopathy

+

Pathological fracture

+

+

+

+

Bone mineral density examination

+

+

+

Protein electrophoresis monoclonal antibody

+

+

PET/CT

 Skeletal abnormalities in different parts of the body

+

+

±

 Mainly abnormal lumbar spine

+

+

±

Pathological section

  1. Note: + means yes, − means no, ± means hard to be sure or negative,? Means that the situation is unknown