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Table 2 Change of parameters after 12-week exenatide treatment in T2DM patients (n = 38)

From: The effect of exenatide on fasting bile acids in newly diagnosed type 2 diabetes mellitus patients, a pilot study

Parameters

Pre-treatment

Exe-treatment

P-value*

Weight, kg

93.1 ± 17.1

86.2 ± 18.1

<0.01

BMI, kg/m2

31.2(28.5–35.1)

29.4(25.3–32.8)

<0.01

TC, mmol/L

5.05 ± 1.11

4.30 ± 0.92

<0.01

HDL-C, mmol/L

1.15 ± 0.46

1.14 ± 0.28

0.899

LDL-C, mmol/L

2.92 ± 0.80

2.57 ± 0.83

<0.01

TG, mmol/L

2.16(1.26–4.21)

1.37(0.94–2.95)

<0.01

FTBAs, μmol/L

3.84 ± 2.06

3.06 ± 1.27

<0.01

HbA1c, %

9.69 ± 2.02

6.51 ± 0.94

<0.01

FPG, mmol/L

9.19 ± 3.46

6.42 ± 1.08

<0.01

FINS, mU/L

9.44 ± 5.22

11.02 ± 4.53

0.128

C-peptide, mU/L

2.83 ± 1.03

3.11 ± 0.84

0.112

HOMA-B

38.81(20.13–61.98)

79.60(48.47–106.09)

<0.01

  1. Data presented as means ± SD or medians (interquartile range)
  2. P-value* were calculated by paired sample t test, exe-treatment vs. pre-treatment