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Table 1 Sociodemographic and clinical characteristics of patients with carbamazepine intoxication. Continuous variables are presented as average ± SEM, ordinal variables are presented as number and percentage

From: The effect of multidrug exposure on neurological manifestations in carbamazepine intoxication: a nested case-control study

 

All patients

Neurological Symptoms

 
 

(n = 80)

Non-Severe (n = 70)

Severe (n = 10)

p-value*

Age (Years)

43.4 ± 2.0

45.2 ± 2.1

30.0 ± 3.5

0.00

Gender (% female)

38 (47.5)

32 (45.7)

4 (40)

0.39

Ethnicity:

   

0.03

 Arab

25 (31.3)

24 (34.3)

1 (10)

 

 Jews

54 (67.5)

46 (66.7)

8 (80)

 

 Others

1 (1.3)

0

1 (10)

 

 Smokers

6 (7.5)

6 (8.9)

0 (0)

0.196

Chronic Carbamazepine users

67 (83.8)

59 (84.3)

8 (80)

0.32

Indications for carbamazepine:

 Epileptic seizures

50 (62.5)

47 (67.1)

4 (40)

0.09

 Psychiatric disorder

27 (33.7)

20 (28.5)

7 (70)

0.013

 Neuropathic pain

4 (5)

4 (5.7)

0 (0)

0.29

 Othersa

5 (6.2)

5 (7.1)

0 (0)

 
  1. *P-value was calculated by t-tests for continuous variables and Chi-square test for ordinal variables
  2. aOthers- primary sclerosis, psychomotor retardation and accidental ingestion