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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Brown adipose tissue activity is modulated in olanzapine-treated young rats by simvastatin

Fig. 2

Effects of olanzapine and/or simvastatin treatment on (a) body weight gain, (b) body temperature, (c) food intake and (d) feeding efficiency of rats over the experiment period. Rats were administrated orally with olanzapine (1 mg/kg, t.i.d), simvastatin (3 mg/kg, t.i.d), co-treatment (O + S) or control (vehicle) for 7 weeks. Data are presented as mean ± SEM (n = 9 per group). *p < 0.05, **p < 0.01 vs. control, #p < 0.05 vs. olanzapine-only group. O + S, co-treatment with olanzapine and simvastatin

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