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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model

Fig. 5

Simulated lisinopril plasma concentration profiles after administration of: (a) 20 mg (b), 10 mg (c), 5 mg (d), 2.5 mg and, (e) 1.5 mg for both genders in infants to toddler as black line, pre-schooled children as blue line, schooled children as green line, adolescent as red line and observed experimental data in healthy adults as dots

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