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Table 3 Listing of all reported unexpected events after 3 or 6 months of cumulative weekly or monthly oral treatment with 800 IU cholecalciferol/day (translated from Swiss German)

From: Oral intermittent vitamin D substitution: influence of pharmaceutical form and dosage frequency on medication adherence: a randomized clinical trial

Preparation

Unexpected event

oily drops

fatigue, but also occurred before

alcoholic drops

possible fatigue, unclear whether there is a connection

oily drops

uncharacteristic abdominal pain

oily drops

shingles: under Vit D considerably less frequent

oily drops

less tired than usual

alcoholic drops

generally feels better under vitamin D, is better off in the morning

oily drops

foot swelling left 1 week ago - now better

oily drops

nervous, palpitations

alcoholic drops

weight loss 7 kg in 2 months (patient report not validated)

alcoholic drops

feeling, I let more water than usual (suspected diuretic effect)

alcoholic drops

heat feeling, feverish, sleep problems

alcoholic drops

had once cramp in the leg

oily drops

less pain in the hand

alcoholic drops

localized itching

alcoholic drops

a little gas (flatulence)

oily drops

possibly more diarrhea (developed over time)

oily drops

at the first 3 doses some nausea after ingestion, spontaneously gone

capsules

approx. 10 days after the 1st ingestion night sweat outbreak (one-time)

oily drops

unique feeling of palpitations