Skip to main content

Table 2 Laboratory findings of the study patients according to hyponatremia (N = 565)

From: Furosemide and spironolactone doses and hyponatremia in patients with heart failure

Laboratory findings Hyponatremic patients (N = 183) Non-hyponatremic patients (N = 382) p
Hemoglobin (median, IQR, g/L) 127 (112–144) 132 (116–144) 0.57
Hematocrit (mean ± SD, L/L) 0.39 ± 0.07 0.4 ± 0.07 0.11
Urea (median, IQR,mmol/L) 10.5 (7–15.5) 8.7 (6.3–12.2) 0.004*
Serum creatinine (median, IQR, mg/dL) 1.4 (1.1–1.9) 1.3 (1–1.7) 0.20
Serum potassium (mean ± SD, mmol/L) 4.3 ± 0.7 4.1 ± 0.6 0.001*
Serum chloride (mean ± SD, mmol/L) 97.2 ± 5.5 101.2 ± 4.4 < 0.001*
Cardiac troponin I (median, IQR, ng/ml) 0.051 (0.020–0.108) 0.039 (0.018–0.089) 0.12
Total cholesterol (median, IQR, mmol/L) 3.4 (3.1–4.9) 4.3 (3.5–5) 0.57
HDL (median, IQR, mmol/L) 1.3 (0.9–1.8) 1.3 (1.3–1.8) 0.71
LDL (median, IQR, mmol/L) 2.4 (1.9–3.2) 2.5 (1.9–3.1) 0.92
Triglycerides (median, IQR, mmol/L) 1.8 (1.4–2.5) 1.8 (1.2–2.4) 0.44
Total bilirubin (median, IQR, μmol/L) 15.9 (11.0–21.0) 14.3 (11.2–18.9) 0.26
Direct bilirubin (median, IQR, μmol/L) 4.0 (2.4–7.0) 4.0 (2.8–6.0) 0.68
Indirect bilirubin (median, IQR, μmol/L) 11.0 (8.6–13.9) 10.2 (8.1–13.1) 0.08
Serum uric acid (median, IQR, μmol/L) 476 (381–574) 440 (367–545) 0.10
AST (median, IQR, μmol/L) 27.0 (19.0–37.0) 24.0 (19.0–33.0) 0.12
ALT (median, IQR, μmol/L) 23.0 (15.8–33.0) 23.0 (17.0–34.3) 0.68
GGT (median, IQR, μmol/L) 45.0 (25.0–97.0) 39.0 (23.0–82.0) 0.16
  1. Hyponatremia: serum sodium < 136 mmol/L, HDL High-density lipoprotein, LDL Low-density lipoprotein, AST Aspartate aminotransferase, ALT Alanine aminotransferase, GGT Gamma-glutamyl transferase
  2. p values refer to the Mann-Whitney U test and t-test as appropriate
  3. * Statistically significant differences (p < 0.05)
\