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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway

Fig. 2

AKBA exhibited similar effect as CDDP on proteins expression and apoptosis in GC cells except for p53. a Western blot shows the effect of AKBA on protein expression in AGS and NCI - N87 cell lines. The expression followed a similar pattern to the cells treated with CDDP b Graphical presentation of apoptosis percentage in AGS and NCI-N87 cell lines treated with different concentrations of AKBA showing significant increase in apoptosis in comparison to control concentration (*P < 0.05, **P < 0.01, ***P < 0.001). The concentration of 100 μM was found to be highly toxic and the apoptosis percentages reached 71.9 and 85.4% in AGS and NCI-N87 cell lines respectively. c Flow cytometry graphs showing the effect of different doses of AKBA on AGS and NCI-N87 cells. Each graph shows alive cells, early and late apoptotic cells, and dead cells

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