Table 2 BoNT/A effects with gene list and fold changes from the DAVID Analysis
DAVID Analysis: Functional Annotation Groups | Gene Title (Gene Symbol) | Fold change 48 h vs. 4 h |
|---|---|---|
Nervous system development | cholinergic receptor, muscarinic 3 (CHRM3) sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 (SPOCK1) neural epidermal growth factor-like EGFL like 1 (NELL1) | 32.28 ↑ 17.07 ↑ 16.95↑ |
Proteinaceous extracellular matrix | collagen, type I, alpha 2 (COL1A2) | 11.99 ↓ |
Signaling pathways regulating pluripotency of stem cells | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein (ID3) inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2) | 8.13 ↓ 31.23 ↓ |
Cellular function and signal Transduction | Rho GTPase activating protein 36 (ARHGAP36) | 11.66↑ |
Apoptosis | insulin like growth factor binding protein 3 (IGFBP3) serum/glucocorticoid regulated kinase 1 (SGK1) | 13.26 ↓ 26.63 ↓ |