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Table 8 E-values for key regression parameters

From: Broad Spectrum epidemiological contribution of cannabis and other substances to the teratological profile of northern New South Wales: geospatial and causal inference analysis

Parameter

Table

Estimate (95%C.I.)

RR

E-Values

Mixed Effects Models

 lme(Congenital_Anomaly ~ Tobacco * Binge_Alcohol * Cannabis)

  Cardiovascular Anomalies

   Atrial_Septal_Defect

    Cannabis

Table 7

0.053 (0.011, 0.096)

1.15 (1.03, 1.29)

1.57, 1.20

  Tetralogy of Fallot

   Cannabis

Table 7

0.079 (0.024, 0.133)

1.18 (1.05, 1.32)

1.63, 1.29

  Gastrointestinal Tract Anomalies

   Cigarettes: Alcohol: Cannabis

Table 7

0.022 (0.004, 0.041)

1.3E+ 160 (3.5E+ 30, 5.1E+ 289)

Infinity, 6.9E+ 30

  Small_Intestinal_Stenosis_Atresia

   Alcohol: Cannabis

Table 7

0.02 (0.008, 0.032)

1.05 (1.02, 1.09)

1.29, 1.16

  Genitourinary Tract Anomalies

   Cigarettes: Alcohol: Cannabis

Table 7

0.008 (0.002, 0.014)

Infinity (6.9E+ 169, Infinity)

Infinity, Infinity

  Chromosomal Anomalies

   Cannabis

Table 7

0.084 (0.019, 0.149)

1.32 (1.06, 1.64)

1.97, 1.33

  Downs_Syndrome

   Cigarettes: Alcohol: Cannabis

Table 7

0.001 (0, 0.001)

1.002 (1.000, 1.004)

1.048, 1.009

 Body Wall Anomalies

  Musculoskeletal

   Cannabis

Table 7

2.686 (0.671, 4.701)

Inf (Inf, Inf)

Infinity, Infinity

  Gastroschisis

   Cannabis

Table 7

0.065 (0.016, 0.115)

1.16 (1.04, 1.30)

1.59, 1.24

  Exomphalos

   Alcohol: Cannabis

Table 7

0.042 (0.002, 0.082)

1.07 (1.0045, 1.15)

1.36, 1.07

Geospatial Models

 spreml(Congenital_Anomaly ~ Tobacco * Binge_Alcohol * Cannabis)

  Atrial_Septal_Defect

   Binge_Alcohol: Cannabis

Table 1

−0.58 (−1.12,-0.03)

0.11 (0.13, 0.87)

17.99, 1.54

   Tobacco: Binge_Alcohol: Cannabis

Table 1

0.03 (0,0.05)

1.11 (1.00, 1.22)

1.45, 1.07

   Tobacco: Cannabis

Table 1

−0.09 (− 0.18,0)

0.71 (0.51, 0.99)

2.17, 1.12

  Tetralogy_Fallot

   Cannabis

Table 1

0.09 (0.04,0.14)

1.21 (1.08, 1.37)

1.73, 1.39

  Ventricular_Septal_Defect

   Tobacco: Cannabis

Table 1

−0.11 (− 0.21,− 0.01)

0.57 (0.34, 0.95)

2.90, 1.27

   Tobacco: Binge_Alcohol: Cannabis

Table 1

0.03 (0,0.06)

1.17 (1.01, 1.37)

1.63, 1.11

  Patent_Ductus_Arteriosus

   Cannabis

Table 1

0.24 (0.02,0.47)

2.63 (1.06, 6.51)

4.71, 1.34

  Chromosomal_Defects

   Tobacco: Binge_Alcohol: Cannabis

Table 1

-0.01 (− 0.01,0)

0.97 (0.95, 0.99)

1.21, 1.13

   Binge_Alcohol: Cannabis

Table 1

0.05 (0.02,0.09)

1.28 (1.09, 1.50)

1.88, 1.42

   Tobacco: Cannabis

Table 1

0.02 (0,0.03)

1.07 (1.02, 1.12)

1.35, 1.16

  Downs Syndrome

   Binge_Alcohol: Cannabis

Table 1

0.03 (0.01,0.04)

1.06 (1.03, 1.10)

1.33, 1.22

  Small Intestinal Stenosis / Atresia

   Cannabis

Table 1

0.02 (0.01,0.03)

1.06 (1.03, 1.10)

1.31, 1.19

  Diaphragmatic_Hernia

   Cannabis

Table 1

7.26 (3.21,11.31)

2.09E+ 09 (1.34E+ 04, 3.27E+ 14)

4.19E+ 09, 2.69E+ 04

   Binge_Alcohol: Cannabis

Table 1

−2.07 (− 3.25,-0.88)

2.21E-03 (6.67E-05, 0.74)

9.00E+ 02, 26.56

   Tobacco: Cannabis

Table 1

−0.22 (− 0.38,-0.07)

0.52 (0.33, 0.81)

3.28, 1.77

   Tobacco: Binge_Alcohol: Cannabis

Table 1

0.06 (0.02,0.11)

1.20 (1.05, 1.36)

1.69, 1.30

  Gastroschisis

   Cannabis

Table 1

0.07 (0.02,0.11)

1.17 (1.06, 1.31)

1.63, 1.30

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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