Table 1 Antibiotic course and clinical outcomes of patients who inject drugs treated with oritavancin
From: Oritavancin for the treatment of complicated gram-positive infection in persons who inject drugs
# | Sex, Age range, BMI | Additional Social History | Infection Location, Source Control Achieved? | Pathogen(s) | Gram- Positive Antibiotics Prior to ORI (days) | Abx DOT before ORI | Concurrent antibiotics with ORI | ORI Doses Planned (received) | Outcome |
|---|---|---|---|---|---|---|---|---|---|
1 | M, 40–49, 22.9 | Homeless | BSI; SSTI Yes | MRSA | VAN × 8 | 8 | None | 1200 × 1 (1) | CC |
2 | M, 40–49, 30.1 | Homeless | Joint Yes | MRSA + Enterobacter | VAN × 1 | 1 | LVX - Enterobacter | 1200 × 2 (2) | CC |
3 | M, 40–49, 20.9 | Homeless ETOH | SSTI N/A | Unknown | None | 0 | None | 1200 × 1 (1) | CC |
4 | F, 40–49, 23.6 | Homeless ETOH | SSTI N/A | MRSA | VAN × 2 | 2 | None | 1200 × 1 (1) | CC |
5 | M, 30–39, 24.5 | ETOH | Joint Yes | MSSA; GAS | CRO × 2 VAN × 1 | 2 | None | 1200 × 1 (1) | CC |
6 | F, 50–59, 39.5 | Homeless ETOH | BSI; SSTI Yes | MSSA | VAN + TZP × 2 NAF × 3 CFZ ×  22 | 25 | None | 1200 × 2 (1) | I/C |
7 | F, 40–49, 19.6 | Homeless ETOH | BSI; Bone Yes | MSSA | LVX × 1 VAN + TZP × 2 CFZ ×  24 | 25 | None | 1200 × 2 (2) | CC |
8 | M, 40–49, 22.8 | Homeless | BSI; Bone; SSTI No | MRSA | VAN × 6 DAL × 1 | 13 | None | 1200 × 1 (1) | CC |
9 | M, 40–49, 32.2 | Homeless | Joint; HW Yes | Strep mitis; Strep oralis | TZP × 3 VAN × 4 CRO × 8 LVX × 8–17 | 36 | None | 1200 × 1 (1) | CC |
10 | F, 30–39, 26.5 |  | BSI; IE No | MSSA | VAN + TZP × 2 NAF × 2 CFZ × 16–23 VAN + TZP ×  2 CFZ × 6 | 30 | None | 1200 × 1 (1) | CC |
11 | M, 50–59, 26.0 |  | BSI; IE; Bone No | MRSA | VAN × 9 CPT + DAP × 14 *none × 4 days* CPT × 5 DAP ×  22 | 47 | None | 1200 × 2 (2) | F |
12 | F, 30–39, 32.5 | Homeless | BSI N/A | MSSA | CRO × 2 VAN × 3 CFZ ×  15 None ×  2 CFZ ×  2 | 20 | None | 1200 × 1 (1) | CC |
13 | M, 40–49, 34.1 | Homeless | BSI N/A | MSSA | VAN × 3 CFZ × 7 CRO × 1 | 10 | None | 1200 × 1 (1) | LTFU |
14 | M, 30–39, 28.9 | Homeless ETOH | BSI; SSTI N/A | MRSA | VAN × 15 DAP ×  1 | 16 | None | 1200 × 2 (2) | LTFU |
15 | M, 60–69, 44.6 |  | Joint; HW No | MRSA, MRSE | VAN × 6 DOX × 5 VAN × 4 | 13 | None | 1200 × 1 (1) 800 × 5 (5) | CC |
16 | F, 20–29, 24.2 | Homeless ETOH | Bone No | MRSA | VAN × 1 | 1 | None | 1200 × 2 (2) | I/C |
17 | M, 20–29, 22.1 | Homeless | Bone; HW No | MSSA | VAN + TZP × 2 CFZ × 2 | 3 | RIF | 1200 × 2 (2) | CC |
18 | M, 30–39, 19.6 | Homeless ETOH | Bone; SSTI Yes | MRSA | VAN × 5 DOX × 2 | 7 | DOX | 1200 × 2 (1) | I/C |
19 | F, 30–39, 36.2 |  | BSI; Bone No | MRSA | VAN × 9 | 9 | None | 1200 × 4 (3) | I/C |
20 | F, 20–29, 23.0 |  | Bone No | MRSA | VAN × 13 | 13 | None | 1200 × 1 (1) 800 × 3 (1) | I/C |
21 | M, 20–29, 23.4 |  | BSI; SSTI N/A | MSSA | VAN × 2 CFZ × 4 | 4 | None | 1200 × 2 (1) | I/F |
22 | M, 40–49, 32.2 | Homeless | Joint Yes | MRSA | VAN × 2 | 2 | RIF | 1200 × 1 (1) 800 × 5 (5) | CC |
23 | M, 30–39, 22.8 | ETOH | BSI N/A | MRSA | VAN × 6 | 6 | None | 1200 × 1 (1) | F |
24 | M, 60–69, 18.0 | Homeless | Bone No | MRSA | DAP × 4 | 4 | None | 1200 × 1 (1) 800 × 3 (3) | CC |