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Table 5 Absolute and relative organ weight of control and treated mice (male and female) in the acute toxicity study of Symplocos racemosa flavonoids

From: Bioprospecting the antimicrobial, antibiofilm and antiproliferative activity of Symplocos racemosa Roxb. Bark phytoconstituents along with their biosafety evaluation and detection of antimicrobial components by GC-MS

 

Absolute organ weight (g)a

 

Relative organ weight (%)a

 

Organs

Control

Treated

p-value

Control

Treated

p-value

   

MALE

   

Liver

0.724 ± 0.031

0.692 ± 0.013

0.365

2.453 ± 0.031

2.441 ± 0.007

0.715

Kidneys

0.401 ± 0.022

0.379 ± 0.015

0.437

1.355 ± 0.035

1.334 ± 0.026

0.638

Heart

0.165 ± 0.007

0.157 ± 0.005

0.390

0.558 ± 0.008

0.577 ± 0.008

0.137

   

FEMALE

   

Liver

0.827 ± 0.044

0.783 ± 0.029

0.435

2.613 ± 0.055

2.653 ± 0.060

0.638

Kidneys

0.410 ± 0.023

0.368 ± 0.006

0.131

1.297 ± 0.031

1.248 ± 0.006

0.179

Heart

0.166 ± 0.0118

0.150 ± 0.004

0.254

0.524 ± 0.0195

0.509 ± 0.009

0.651

  1. aData indicate Mean ± SEM (n = 6 for each group). There was no significant difference between the test and control groups as indicated by Post hoc Tukey’s t-test
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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