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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation

Fig. 5

The PD-induced reduction in systemic bone formation was reversed by LLP2A-Ale+/− MSCs. a Representative distal femoral metaphysis images in each group. All mice received double calcein labeling before euthanization (green arrows). White arrows indicate some transplanted td-Tomato+ MSCs, some of which were positive for calcein and appeared yellow (yellow arrow). b Quantitative measurements of the trabecular bone area, mineral apposition rate, and surface-based bone formation rate at the right distal femur. * p < 0.05 for comparisons of the indicated groups

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