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Table 1 Effect of continentalic acid on CBC

From: Attenuation of LPS-induced acute lung injury by continentalic acid in rodents through inhibition of inflammatory mediators correlates with increased Nrf2 protein expression

Parameters

WBC count

(109/L)

LYM

(109/L)

NEU

(109/L)

RBC

(1012/L)

PLT

(109/L)

Vehicle control

4.4 ± 0.17

3.6 ± 0.90

2.5 ± 0.12

4.62 ± 0.19

189 ± 10

LPS treated

8.5 ± 0.11###

6.9 ± 0.17###

6.5 ± 0.08 ###

4.41 ± 0.13###

185 ± 16###

LPS + Vehicle

8.34 ± 0.20###

7.12 ± 0.05###

6.7 ± 0.10 ###

4.32 ± 0.41###

184 ± 8###

Dexa 10 mg/kg

4.5 ± 0.21***

3.8 ± 0.11

2.60 ± 0.12***

4.49 ± 0.30

183 ± 10

CNT 10 mg/kg

6.5 ± 0.23

4.90 ± 0.09

5.01 ± 0.12

4.34 ± 0.11

189 ± 22

CNT 50 mg/kg

4.8 ± 0.15**

4.30 ± 0.12

2.70 ± 0.15**

4.51 ± 0.40

188 ± 13

CNT 100 mg/kg

4.4 ± 0.10***

3.70 ± 0.15

2.62 ± .90 ***

4.50 ± 0.09

182 ± 9

  1. All data were expressed as mean (n = 8) ± SD
  2. ###p < 0.001compared to control group
  3. ***p < 0.001compared to negative control group