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Table 2 Pharmacokinetic parameters of levamlodipine test and reference formulations in the fasted group (n = 24)

From: Bioequivalence of levamlodipine besylate tablets in healthy Chinese subjects: a single-dose and two-period crossover randomized study

Parameter

Arithmetic mean ± SD (%CV)a

T

R

Cmax/μg × L−1

2.70 ± 0.490 (18.2%)

2.83 ± 0.516 (18.2%)

AUC0–t/μg × h × L− 1

141.32 ± 36.24 (25.65%)

153.62 ± 33.96 (22.10%)

AUC0–∞/μg × h × L− 1

157.14 ± 45.65 (29.05%)

173.05 ± 41.78 (24.15%)

T1/2/h

49.46 ± 11.35 (22.95%)

52.92 ± 14.51 (27.42%)

tmax*/h

6.00 (2.00, 8.00)

6.00 (3.00, 12.00)

  1. aAll values are represented as arithmetic mean ± standard deviation (CV, %) with [geometric mean] unless otherwise specified. *tmax is shown as median (minimum-maximum)