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Table 3 Pharmacokinetic parameters of levamlodipine test and reference formulations in the fed group (n = 24)

From: Bioequivalence of levamlodipine besylate tablets in healthy Chinese subjects: a single-dose and two-period crossover randomized study

Parameter

Arithmetic mean ± SD (%CV)a

T

R

Cmax/μg × L−1

2.73 ± 0.547 (20.1%)

2.87 ± 0.812 (28.3%)

AUC0–t/μg × h × L− 1

166.93 ± 49.96 (29.93%)

165.46 ± 43.58 (26.34%)

AUC0–∞/μg × h × L− 1

190.99 ± 70.89 (37.12%)

189.51 ± 64.70 (34.14%)

T1/2/h

53.38 ± 10.99 (20.58%)

53.56 ± 13.41 (25.05%)

tmax*/h

7.00 (5.00, 14.00)

7.00 (2.00, 24.00)

  1. aAll values are represented as arithmetic mean ± standard deviation (CV, %) with [geometric mean] unless otherwise specified. *tmax is shown as median (minimum-maximum)
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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