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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: Nebivolol combined with tetrahydrobiopterin affects diastolic function in spontaneously hypertensive rats via the nitric oxide/cyclic guanosine monophosphate signalling pathway

Fig. 4

eNOS and eNOS dimer expression in myocardium. a The relative mRNA of eNOS in myocardium, BH4 combined with nebivolol treatment can significantly increase myocardial eNOS mRNA expression. b The relative protein expression of eNOS in myocardium, BH4 combined with nebivolol treatment can significantly increase the expression of eNOS protein in myocardium. c The relative protein expression of eNOS in myocardium. d The relative protein expression of eNOS dimer in myocardium. e eNOS activity in myocardium, high-dose BH4 combined with high-dose nebivolol can significantly increase eNOS activity. f The production of NO in myocardium .*P < 0.01 versus Control, # p < 0.01 versus L-N&L-BH4

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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