Fig. 6From: Nebivolol combined with tetrahydrobiopterin affects diastolic function in spontaneously hypertensive rats via the nitric oxide/cyclic guanosine monophosphate signalling pathwayBH4 combined with Nebivolol promote the expression level of cGMP in myocardium. a The expression of cGMP in myocardium was detected by immunohistochemistry (n = 20), and the scale was 100 μm. b Statistics of cGMP expression in the myocardium, the data are expressed as the mean density of Image-Pro plus. c The expression of cGMP in myocardium was detected by ELISA.*P < 0.01 versus Control, # p < 0.01 versus L-N&L-BH4Back to article page