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Table 4 Demographic profile of patients for stages 1 and 2

From: Pharmacokinetic study of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement product

 

Treatment Groups

Stage 1

N = 8

Stage 2

N = 26

Age (years)

 Mean ± SD

34 ± 9

35 ± 9

 Median

37.0

33.0

 Range

21–44

22–55

 Groups

n (%)

n (%)

 < 18

0 (0%)

0 (0%)

 18 – 40

5 (62.5%)

19 (73.1%)

 40 – 64

3 (37.5%)

7 (26.9%)

 65 – 75

0 (0%)

0 (0%)

 > 75

0 (0%)

0 (0%)

Sex

 Female

0 (0%)

19 (73.1%)

 Male

8 (100)

7 (26.9%)

Race

 Asian

1 (12.5%)

0 (0%)

 Black

1 (12.5%)

4 (15.4%)

 Caucasian

6 (75.0%)

22 (84.6%)

 Other

0 (0%)

0 (0%)

Weight (kg)

 Mean ± SD

74.6 ± 10.7

64.0 ± 11.6

 Median

76.9

61.30

 Range

57.7–92.8

48.4–98.0

Height (cm)

 Mean ± SD

175.3 ± 10.1

164.1 ± 9.8

 Median

175.25

161.25

 Range

158.5–189.0

149.0–189.0

Body Mass Index (kg/m2)

 Mean ± SD

24.29 ± 2.72

23.63 ± 2.28

 Median

24.77

23.39

 Range

19.79–27.97

20.15–28.29