Table 4 The top 20 drugs contributing to anticholinergic burden measured by each scale

1

ranitidine^a

11.4

1

ranitidine^a

29.8

1

hydrochlorothiazide

15.7

2

ranitidine^a

24.3

3

dimenhydrinate

8.0

3

chlorpheniramine^a

18.8

1

ranitidine^a

10.3

3

dimenhydrinate

8.6

3

chlorpheniramine^a

7.2

2

cimetidine^a

12.8

3

dimenhydrinate

7.2

3

chlorpheniramine^a

7.7

2

tramadol

6.7

3

amitriptyline^a

4.7

3

chlorpheniramine^a

6.5

2

cimetidine^a

5.2

3

solifenacin

6.4

2

cetirizine

4.5

3

solifenacin

5.7

1

furosemide

5.0

2

cimetidine^a

4.9

1

levodopa

4.3

1

furosemide

4.2

1

isosorbide

4.3

1

furosemide

4.7

2

tolterodine^a

3.9

1

isosorbide

3.6

1

tramadol

3.6

3

propiverine

3.5

3

hydroxyzine^a

2.6

3

propiverine

3.1

1

nifedipine

3.3

1

escitalopram

3.2

2

amantadine^a

1.7

1

escitalopram

2.8

1

alprazolam

3.2

1

alprazolam

3.0

1

paroxetine^a

1.6

1

nifedipine

2.8

3

tolterodine^a

2.4

3

octylonium^b

2.6

3

butylscopolamine^a

1.4

1

alprazolam

2.7

1

diltiazem

2.3

1

levocetirizine

2.5

2

loratadine

1.2

1

atenolol

2.4

1

famotidine

2.0

1

trimebutine^b

2.3

2

nortriptyline^a

1.2

1

levocetirizine

2.3

1

nizatidine

1.9

3

tolterodine^a

2.3

1

mirtazapine

1.2

1

cimetidine^a

2.2

3

amitriptyline^a

1.9

3

fesoterodine

2.0

3

imipramine^a

1.2

3

tolterodine^a

2.0

1

prednisolone

1.9

3

amitriptyline^a

1.8

1

quetiapine^a

1.1

1

doxazosin

1.8

1

methylprednisolone

1.8

1

prednisolone

1.8

2

baclofen

0.9

3

fesoterodine

1.8

1

diazepam

1.8

1

diazepam

1.6

2

loperamide^a

0.9

3

paroxetine^a

1.7

1

digoxin

1.6

1

digoxin

1.5

1

trazodone

0.9

3

amitriptyline^a

1.6

1

dexamethasone

1.3

2

paroxetine^a

1.2

2

olanzapine^a

0.8

1

prednisolone

1.6

1

lorazepam

1.3