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Table 4 The top 20 drugs contributing to anticholinergic burden measured by each scale

From: Comparative associations between anticholinergic burden and emergency department visits for anticholinergic adverse events in older Korean adults: a nested case-control study using national claims data for validation of a novel country-specific scale

KABS ARS ACB ADS
Score Drug % Score Drug % Score Drug % Score Drug %
1 ranitidinea 11.4 1 ranitidinea 29.8 1 hydrochlorothiazide 15.7 2 ranitidinea 24.3
3 dimenhydrinate 8.0 3 chlorpheniraminea 18.8 1 ranitidinea 10.3 3 dimenhydrinate 8.6
3 chlorpheniraminea 7.2 2 cimetidinea 12.8 3 dimenhydrinate 7.2 3 chlorpheniraminea 7.7
2 tramadol 6.7 3 amitriptylinea 4.7 3 chlorpheniraminea 6.5 2 cimetidinea 5.2
3 solifenacin 6.4 2 cetirizine 4.5 3 solifenacin 5.7 1 furosemide 5.0
2 cimetidinea 4.9 1 levodopa 4.3 1 furosemide 4.2 1 isosorbide 4.3
1 furosemide 4.7 2 tolterodinea 3.9 1 isosorbide 3.6 1 tramadol 3.6
3 propiverine 3.5 3 hydroxyzinea 2.6 3 propiverine 3.1 1 nifedipine 3.3
1 escitalopram 3.2 2 amantadinea 1.7 1 escitalopram 2.8 1 alprazolam 3.2
1 alprazolam 3.0 1 paroxetinea 1.6 1 nifedipine 2.8 3 tolterodinea 2.4
3 octyloniumb 2.6 3 butylscopolaminea 1.4 1 alprazolam 2.7 1 diltiazem 2.3
1 levocetirizine 2.5 2 loratadine 1.2 1 atenolol 2.4 1 famotidine 2.0
1 trimebutineb 2.3 2 nortriptylinea 1.2 1 levocetirizine 2.3 1 nizatidine 1.9
3 tolterodinea 2.3 1 mirtazapine 1.2 1 cimetidinea 2.2 3 amitriptylinea 1.9
3 fesoterodine 2.0 3 imipraminea 1.2 3 tolterodinea 2.0 1 prednisolone 1.9
3 amitriptylinea 1.8 1 quetiapinea 1.1 1 doxazosin 1.8 1 methylprednisolone 1.8
1 prednisolone 1.8 2 baclofen 0.9 3 fesoterodine 1.8 1 diazepam 1.8
1 diazepam 1.6 2 loperamidea 0.9 3 paroxetinea 1.7 1 digoxin 1.6
1 digoxin 1.5 1 trazodone 0.9 3 amitriptylinea 1.6 1 dexamethasone 1.3
2 paroxetinea 1.2 2 olanzapinea 0.8 1 prednisolone 1.6 1 lorazepam 1.3
  1. KABS Korean Anticholinergic Burden Scale, ARS Anticholinergic Risk Scale, ACB Anticholinergic Cognitive Burden, ADS Anticholinergic Drug Scale
  2. aDrugs common to all four anticholinergic drug scales
  3. bDrugs included only in the KABS list