Table 2 Downregulated genes in Cy-exposed mice
From: Extended adverse effects of cyclophosphamide on mouse ovarian function
Fold Change | p-value | Gene Symbol | Description |
|---|---|---|---|
4.92 | 0.0009 | Ighv10–1 | Immunoglobulin heavy variable 10–1 |
4.71 | 0.0402 | Igk-V1 | Immunoglobulin kappa chain variable 1 |
4.49 | 0.0204 | Igkv6–14 | Immunoglobulin kappa variable 6–14 |
4.05 | 0.0095 | Ighv1–62-2 | Immunoglobulin heavy variable 1–62-2 |
4.05 | 0.0095 | Ighv1–71 | Immunoglobulin heavy variable 1–71 |
3.71 | 0.0235 | Igh-VJ558 | Immunoglobulin heavy chain (J558 family) |
3.25 | 0.0402 | Ighv5–16 | Immunoglobulin heavy variable 5–16 |
3.19 | 0.0184 | Igkv5–45 | Immunoglobulin heavy chain variable 5–45 |
2.93 | 0.0003 | Nlrp14 | NLR family, pyrin domain containing 14 |
2.79 | 0.0003 | Oas1d | 2–5 oligoadenylate synthetase 1D |
2.70 | 0.0009 | Slc38a3 | solute carrier family 38, member 3 |
2.65 | 0.0203 | Mug-ps1 | Murinoglobulin, pseudogene 1 |
2.63 | 0.0049 | Igkv8–28 | Immunoglobulin kappa variable 8–28 |
2.59 | 3.59E-05 | Zp2 | zona pellucida glycoprotein 2 |
2.56 | 0.0001 | Nlrp5 | NLR family, pyrin domain containing 5 |
2.54 | 0.0002 | Khdc1b | KH domain containing 1B |
2.45 | 0.0009 | Khdc1a | KH domain containing 1A |
2.45 | 0.0266 | n-R5s71 | nuclear encoded rRNA 5S 71 [Source:MGI Symbol;Acc:MGI:4421916] |
2.41 | 0.0056 | Gm6205 | predicted gene 6205 |
2.38 | 0.0007 | Dynap | dynactin associated protein |
2.31 | 0.0048 | Slc18a2 | solute carrier family 18 (vesicular monoamine), member 2 |
2.27 | 0.0023 | Gm4541 | Predicted gene 4541 |
2.25 | 0.0025 | Txndc2 | Thioredoxin domain containing 2 |
2.2 | 0.0021 | Wee2 | WEE1 homolog 2 |
2.19 | 0.0004 | Nlrp9c | NLR family, pyrin domain containing 9C |
2.18 | 0.165 | Khdc1c | KH domain containing 1C |
2.16 | 0.0003 | Padi6 | peptidyl arginine deiminase, type VI |
2.15 | 8.81E-05 | Gm1965 | predicted gene 1965 |
2.14 | 0.005 | Obox1 | Oocyte specific homeobox 1 |
2.14 | 0.007 | Tcl1b1 | T cell leukemia/lymphoma 1B, 1 |
2.12 | 0.0002 | Tcl1b3 | T cell leukemia/lymphoma 1B, 3 |
2.12 | 0.0036 | Gm6900 | Predicted gene 6900 [Source:MGI Symbol;Acc:MGI:3645052] |
2.11 | 0.0003 | Fbxw19 | F-box and WD-40 domain protein 19 |
2.08 | 0.0082 | Fbxw15 | F-box and WD-40 domain protein 15 |
2.07 | 0.0193 | Ighv1–62-1 | Immunoglobulin heavy variable 1–62-1 |
2.05 | 0.0025 | Fbxw18 | F-box and WD-40 domain protein 18 |
2.05 | 0.0084 | Mir1901 | microRNA 1901 |
2.02 | 0.0003 | Zp3 | zona pellucida glycoprotein 3 |
2.31 | 0.0053 | Oas1e | 2–5 oligoadenylate synthetase 1E |