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Fig. 6 | BMC Pharmacology and Toxicology

Fig. 6

From: Improved effect of a mitochondria-targeted antioxidant on hydrogen peroxide-induced oxidative stress in human retinal pigment epithelium cells

Fig. 6

Involvement of PGC-1α/NRF2/NQO1/HO-1 axis for antioxidant effects of TPP-Niacin. Gene expression analysis by qPCR of transcription factors (a) and major antioxidant related genes (b). All gene expression data were analyzed using Student’s t-test. Statistical significance is represented as follows: # P < 0.05, ### P < 0.01 versus control group; P < 0.05, P < 0.01, and P < 0.001 versus the H2O2-treated group

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