Fig. 6
Involvement of PGC-1α/NRF2/NQO1/HO-1 axis for antioxidant effects of TPP-Niacin. Gene expression analysis by qPCR of transcription factors (a) and major antioxidant related genes (b). All gene expression data were analyzed using Student’s t-test. Statistical significance is represented as follows: # P < 0.05, ### P < 0.01 versus control group; ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 versus the H2O2-treated group