Fig. 3

Silibinin treatment reversed inflammatory phenotype toward anti-inflammatory gene expression. Adipose tissue gene expression levels of inflammatory cells markers F4/80 and CD11c (a), proinflammatory cytokines TNF-a, IL-1β and IL-6 (b), anti-inflammatory cytokine IL-10 (c) and the adipokines leptin and adiponectin (d). Values represent averages ± SD (n = 5). *: P < 0.05, **: P < 0.01, ns: nonsignificant