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Table 1 Chemical compounds used during this study

From: Are antibiotics substandard in Lebanon? Quantification of active pharmaceutical ingredients between brand and generics of selected antibiotics

Chemical Compounds

Structurea

Formula

CAS number

Purity

Supplier

Ciprofloxacin hydrochloride (reference standard)

C17H19ClFN3O3

85,721–33-1

Pharmaceutical secondary standard; certified reference material

Sigma-Aldrich

Methanol

CH4O

67–56-1

≥99.9% (Chromasolv, for HPLC)

Honeywell (Riedel-de Haën)

Acetonitrile

C2H3N

75–05-8

≥99.9% (Chromasolv gradient, for HPLC, gradient grade)

Honeywell (Riedel-de Haën)

Phosphoric acid

H3O4P

7664-38-2

98% (ACS reagent, reagent ISO)

Sigma-Aldrich

Triethylamine

C6H15N

121–44-8

99%

Scharlau

Amoxicillin trihydrate

C16H19N3O5S .3 H2O

61,336–70-7

Pharmaceutical Secondary Standard; Certified Reference Material

Sigma-Aldrich

Potassim clavulanate

C8H8NO5K

61,177–45-5

VETRANALâ„¢

Analytical standard

Sigma-Aldrich

  1. aSource for structures: American Chemical Society. Source for Ciprofloxacin structure: US FDA
  2. Name and address of the companies that provided the compounds:
  3. 1) Name: Ibra HadadAddress: Jdeideh – Nahr El Mott, UniLeb Building, 2nd Floor.ibra@ibrahadad.comCompounds provided: ciprofloxacin hydrochloride (reference standard), acetonitrile, methanol, phosphoric acid, amoxicillin trihydrate, potassium clavulanate. Compounds purchased from: the United States of America
  4. 2) Name: BioDiagnosticAddress: El Bouchrieh Industrial City, Saint Jean Center, 2nd Floor.www.biodiagnostic-lb.comCompound provided: triethylamine.Compound purchased from: Spain