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Table 2 Amount in mg of ciprofloxacin in the tested weighed mass (runs 1, 2 and 3)

From: Are antibiotics substandard in Lebanon? Quantification of active pharmaceutical ingredients between brand and generics of selected antibiotics

MedicineBatch numberMass of unknown sample (mg)Mass of ciprofloxacin (CIP) per tablet (mg)Mean amount of ciprofloxacin (CIP) per tablet (mg)SD (a)RSD (b) (%)Relative deviation© (%)USP requirement
Drug 1.1 (run 1)BXJ1KK2 BXJ22L1762.7464.8028473.6614.453.05−5.2798–102%
Drug 1.2762.8465.8469
Drug 1.3762.9490.3392
Drug 4.10802138 0802139762.2482.6215474.387.251.53−5.1298–102%
Drug 4.2762.4468.9408
Drug 4.3762.4471.5772
Drug 5.1M101 M102763.5461.0619466.706.331.35−6.6698–102%
Drug 5.2763.6465.4737
Drug 5.3763.6473.5532
Drug 3.1 (run 2)NOB51 N2KX1824.2537.1647543.7813.892.558.7698–102%
Drug 3.2824.4534.4266
Drug 3.3824.2559.7423
Drug 3 (2).1M12A1 M3R01824.7536.2957525.3311.152.125.0798–102%
Drug 3 (2).2824.8514.0106
Drug 3 (2).3824.9525.6963
Drug 3 (3).1N2 L01 N2KX1822.8524.1745529.4517.123.235.8998–102%
Drug 3 (3).2822.9515.5925
Drug 3 (3).3822.9548.5816
Drug 2.14710 2966773.9485.4494483.552.180.45−3.2998–102%
Drug 2.2773.8481.1726
Drug 2.3773.7484.0210
Drug2 [1].1(run 3)5006 5006774.2493.3421495.703.420.69−0.8698–102%
Drug 2 (1).2774.1499.6229
Drug 2 (1).3774.1494.1410
Drug 2 (2).14710 5006772.9491.9032487.385.941.22−2.5298–102%
Drug 2 (2).2772.8480.6563
Drug 2 (2).3772.8489.5944
  1. a: SD = \( \sqrt{\frac{\sum \left(x-\overline{x}\right)}{n}} \) b: RSD = \( \frac{SD\ }{\overline{X}}\times 100 \) c: RD = \( \frac{experimental- expected}{expected} \)