Table 2 Amount in mg of ciprofloxacin in the tested weighed mass (runs 1, 2 and 3)
Medicine | Batch number | Mass of unknown sample (mg) | Mass of ciprofloxacin (CIP) per tablet (mg) | Mean amount of ciprofloxacin (CIP) per tablet (mg) | SD (a) | RSD (b) (%) | Relative deviation© (%) | USP requirement |
|---|---|---|---|---|---|---|---|---|
Drug 1.1 (run 1) | BXJ1KK2 BXJ22L1 | 762.7 | 464.8028 | 473.66 | 14.45 | 3.05 | −5.27 | 98–102% |
Drug 1.2 | 762.8 | 465.8469 | ||||||
Drug 1.3 | 762.9 | 490.3392 | ||||||
Drug 4.1 | 0802138 0802139 | 762.2 | 482.6215 | 474.38 | 7.25 | 1.53 | −5.12 | 98–102% |
Drug 4.2 | 762.4 | 468.9408 | ||||||
Drug 4.3 | 762.4 | 471.5772 | ||||||
Drug 5.1 | M101 M102 | 763.5 | 461.0619 | 466.70 | 6.33 | 1.35 | −6.66 | 98–102% |
Drug 5.2 | 763.6 | 465.4737 | ||||||
Drug 5.3 | 763.6 | 473.5532 | ||||||
Drug 3.1 (run 2) | NOB51 N2KX1 | 824.2 | 537.1647 | 543.78 | 13.89 | 2.55 | 8.76 | 98–102% |
Drug 3.2 | 824.4 | 534.4266 | ||||||
Drug 3.3 | 824.2 | 559.7423 | ||||||
Drug 3 (2).1 | M12A1 M3R01 | 824.7 | 536.2957 | 525.33 | 11.15 | 2.12 | 5.07 | 98–102% |
Drug 3 (2).2 | 824.8 | 514.0106 | ||||||
Drug 3 (2).3 | 824.9 | 525.6963 | ||||||
Drug 3 (3).1 | N2 L01 N2KX1 | 822.8 | 524.1745 | 529.45 | 17.12 | 3.23 | 5.89 | 98–102% |
Drug 3 (3).2 | 822.9 | 515.5925 | ||||||
Drug 3 (3).3 | 822.9 | 548.5816 | ||||||
Drug 2.1 | 4710 2966 | 773.9 | 485.4494 | 483.55 | 2.18 | 0.45 | −3.29 | 98–102% |
Drug 2.2 | 773.8 | 481.1726 | ||||||
Drug 2.3 | 773.7 | 484.0210 | ||||||
Drug2 [1].1(run 3) | 5006 5006 | 774.2 | 493.3421 | 495.70 | 3.42 | 0.69 | −0.86 | 98–102% |
Drug 2 (1).2 | 774.1 | 499.6229 | ||||||
Drug 2 (1).3 | 774.1 | 494.1410 | ||||||
Drug 2 (2).1 | 4710 5006 | 772.9 | 491.9032 | 487.38 | 5.94 | 1.22 | −2.52 | 98–102% |
Drug 2 (2).2 | 772.8 | 480.6563 | ||||||
Drug 2 (2).3 | 772.8 | 489.5944 |