Are antibiotics substandard in Lebanon? Quantification of active pharmaceutical ingredients between brand and generics of selected antibiotics

Table 3 Amount in mg of amoxicillin in the tested weighed mass

Medicine	Mass of unknown sample	Mass of amoxicillinper pill	Mean amount of amox (mg)	SD ^(a)	RSD ^(b) (%)	Relative deviation (%)©	USP requirement
Drug1.1	0.5886	544.29	547.14	2.60	0.47	9.42	90–120%
Drug1.2	0.581	549.42
Drug1.3	0.5832	547.705
Drug2.1	0.6058	554.11	556.90	4.55	0.81	11.38	90–120%
Drug2.2	0.6022	554.44
Drug2.3	0.6068	562.16
Drug3.1	0.6058	551.62	549.67	5.41	0.98	9.93	90–120%
Drug3.2	0.6022	553.83
Drug3.3	0.6068	543.55

a: SD = \( \sqrt{\frac{\sum \left(x-\overline{x}\right)}{n}} \) b: RSD = \( \frac{SD\ }{\overline{X}}\times 100 \) c: RD = \( \frac{experimental- expected}{expected} \)

ISSN: 2050-6511