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Table 2 Reported seriousness criteria per 100,000 inhabitants in the stratified age groups

From: Adverse drug reactions in older adults: a retrospective comparative analysis of spontaneous reports to the German Federal Institute for Drugs and Medical Devices

 Patients aged 66–75 years (n = 37,370)Patients aged 76–84 years (n = 22,761)Patients aged ≥85 years (n = 7036)
ADR reports per 100,000 inhabitants
 female23.7 (+/−  6.1)24.4 (+/−  7.6)19.5 (+/−  7.7)
 males24.0 (+/−  6.8)26.4 (+/−  7.6)23.7 (+/−  8.3)
ADR reports “serious” per 100,000 inhabitants
 female19.2 (+/−  6.2)20.6 (+/−  8.0)17.2 (+/−  8.0)
 male20.1 (+/−  6.5)22.8 (+/−  7.7)21.0 (+/−  8.1)
ADR reports “death” per 100,000 inhabitants
 female1.4 (+/−  0.6)2.4 (+/−  1.6)3.0 (+/− 3.2)
 male2.0 (+/−  0.6)3.0 (+/−  1.2)3.5 (+/−  2.4)
ADR reports “hospitalisation” per 100,000 inhabitants
 female8.8 (+/−  2.6)10.9 (+/−  4.9)9.6 (+/−  5.2)
 male9.6 (+/−  2.6)11.7 (+/−  4.0)10.9 (+/−  3.9)
ADR reports “life-threatening” per 100,000 inhabitants
 female2.5 (+/−  0.8)3.3 (+/−  1.5)3.1 (+/− 2.2)
 male3.2 (+/−  0.9)3.7 (+/− 1.3)3.5 (+/−  1.8)
  1. Table 2 shows the average number (+/− SD) of ADR reports per 100,000 German inhabitants distributed by gender and reported seriousness criteria. The age groups were adapted for this analysis since inhabitants older than 85 years could not be stratified further in the database queried [23]. One ADR report may inform about more than one seriousness criteria. Hence, one ADR reports can be assigned to several seriousness criteria