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Table 2 Hemodynamic and laboratory data in Experiment 2

From: Effects of β1-adrenergic receptor blockade on the cerebral microcirculation in the normal state and during global brain ischemia/reperfusion injury in rabbits

 MAPHRpHBEPaCO2PaO2NaKGlucose
 (mmHg)(beats/min)  (mmHg)(mmHg)(mEq/L)(mEq/L)(mg/dL)
Control group
 baseline107 ± 15306 ± 457.43 ± 0.05− 0.7 ± 2.140.0 ± 5.6179 ± 14141 ± 23.3 ± 0.3141 ± 18
 ischemia115 ± 35303 ± 557.37 ± 0.08−6.3 ± 4.235.2 ± 9.0115 ± 60140 ± 43.7 ± 0.5272 ± 84
 Unclamp 5 min91 ± 44289 ± 527.30 ± 0.08−7.3 ± 3.141.2 ± 3.7160 ± 35140 ± 33.7 ± 0.2272 ± 88
 Unclamp 10 min88 ± 36301 ± 597.30 ± 0.09−7 ± 2.641.8 ± 4.6148 ± 28139 ± 23.4 ± 0.2273 ± 110
 Unclamp 20 min86 ± 34297 ± 597.32 ± 0.06−6.8 ± 2.341.5 ± 0.6152 ± 26138 ± 23.5 ± 0.4268 ± 116
 Unclamp 40 min77 ± 29289 ± 557.35 ± 0.06− 5.1 ± 3.539.2 ± 2.0160 ± 33139 ± 43.6 ± 0.5242 ± 111
 Unclamp 60 min74 ± 25282 ± 497.37 ± 0.05− 3.7 ± 2.338.7 ± 1.8170 ± 22139 ± 33.9 ± 0.5214 ± 87
 Unclamp 80 min79 ± 29281 ± 487.38 ± 0.05−3.1 ± 3.138.0 ± 1.8167 ± 37140 ± 34.0 ± 0.6196 ± 73
 Unclamp 100 min78 ± 29284 ± 577.38 ± 0.06−4.3 ± 3.236.5 ± 2.8158 ± 29140 ± 24.0 ± 0.6176 ± 53
 Unclamp 120 min79 ± 33294 ± 757.38 ± 0.07−4.6 ± 3.136.1 ± 2.6165 ± 36140 ± 44.0 ± 0.5167 ± 44
Landiolol group
 baseline91 ± 27290 ± 337.43 ± 0.051.0 ± 1.238.2 ± 4.3162 ± 37143 ± 33.1 ± 0.5131 ± 36
 ischemia122 ± 35322 ± 907.34 ± 0.02− 8.0 ± 1.431.7 ± 4.9140 ± 32141 ± 53.8 ± 1.1200 ± 73
 Unclamp 5 min90 ± 17295 ± 517.22 ± 0.04− 9.3 ± 3.044.3 ± 4.2141 ± 36141 ± 53.5 ± 0.5203 ± 56
 Unclamp 10 min96 ± 9298 ± 457.23 ± 0.05− 9.5 ± 3.343.3 ± 4.7143 ± 48141 ± 33.4 ± 0.6209 ± 65
 Unclamp 20 min88 ± 12290 ± 587.26 ± 0.09− 9.3 ± 3.239.5 ± 4.2139 ± 35141 ± 43.3 ± 0.6205 ± 59
 Unclamp 40 min96 ± 11294 ± 537.28 ± 0.10− 7.5 ± 3.140.9 ± 6.2128 ± 35141 ± 43.4 ± 0.7211 ± 89
 Unclamp 60 min84 ± 6294 ± 537.30 ± 0.06− 6.0 ± 4.041.2 ± 3.8134 ± 50140 ± 43.6 ± 1.0201 ± 106
 Unclamp 80 min81 ± 13295 ± 497.31 ± 0.08− 5.5 ± 5.140.7 ± 3.5164 ± 43140 ± 33.5 ± 0.7204 ± 133
 Unclamp 100 min75 ± 18291 ± 497.32 ± 0.11−4.8 ± 5.740.5 ± 3.4139 ± 61141 ± 33.6 ± 0.8166 ± 66
 Unclamp 120 min73 ± 14295 ± 557.34 ± 0.11−4.5 ± 5.738.9 ± 4.0123 ± 43140 ± 43.6 ± 0.9162 ± 64
  1. Values are expressed as mean ± SD
  2. MAP significantly increased after clamping the brachiocephalic artery, left common carotid artery, and left subclavian artery both in the control and landiolol groups. In contrast, HR remained largely unchanged in both groups. After unclamping, MAP, HR, and BE decreased. Plasma glucose increased significantly. There were no significant differences in the hemodynamic and physiological variables between groups
  3. MAP mean arterial pressure; HR heart rate; BE base excess