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Table 2 Expression of NF-κB subunit genes involved in multidrug resistance in HL-60/5FU cells

From: New uracil analog U-332 is an inhibitor of NF-κB in 5-fluorouracil-resistant human leukemia HL-60 cell line

gene

c-Rel

RelA

RelB

NF-κB1

NF-κB2

Control (HL-60)

1.0 ± 0.02

1.0 ± 0.01

1.0 ± 0.08

1.0 ± 0.02

1.0 ± 0.02

HL-60/5FU

4.4 ± 0.2***

2.1 ± 0.1***

1.1 ± 0.04

2.9 ± 0.1***

1.2 ± 0.05

  1. Data represent mean ± SEM of three independent experiments performed in triplicate. ***, p < 0.001
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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