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Table 5 Factors associated to permanent renal toxicity at univariable analysis

From: Risk factors for renal toxicity after inpatient cisplatin administration

 

N (%)

p-value

Sex

 Male

13 (13)

0.60

 Female

8 (10)

Smoke

 No

6 (8)

0.049

 Yes

12 (20)

 Former Smokers

2 (6)

Alcohol

 No

18 (12)

0.98

 Yes

3 (12)

Diuretic

 No

10 (10)

0.55

 During Cisplatin

10 (16)

 Before of after Cisplatin

1 (9)

ACE-Inhibitor

 No

20 (12)

0.61

 Yes

1 (7)

Metformin

 No

20 (12)

0.58

 Yes

1 (20)

ICM

 No

17 (11)

0.58

 Yes

4 (15)

Obesity

 No

1 (5)

0.57

 Yes

1 (12)

Dyslipidemia

 No

16 (10)

0.08

 Yes

5 (23)

Diabetes

 No

20 (12)

0.83

 Yes

1 (10)

Cardiopathy

 No

21 (13)

0.18

 Yes

0 (0)

Vasculopathy

 No

18 (11)

0.60

 Yes

3 (15)

COPD

 No

18 (11)

0.60

 Yes

3 (15)

Hypertension

 No

12 (10)

0.19

 Yes

9 (16)

Cirrhosis

 No

20 (11)

0.42

 Yes

1 (25)

Hypoalbuminemia

 No

15 (14)

0.70

 Yes

3 (18)

NSAID

 No

13 (8)

0.002

 Yes

8 (29)

  1. Legend: COPD Chronic obstructive pulmonary disease, ICM Iodinated contrast media, NSAID Non-steroidal anti-inflammatory drug, ACE-Inhibitor Angiotensin converting enzyme inhibitor, N Number of patients