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Table 1 Effects of different brimonidine eye drops formulations on neutrophil migration

From: The chemotactic properties of various topical brimonidine tartrate ophthalmic preparations

Drugs (1:100 dilution)

Migration distance ± SD (μm)

BT 0.2% with BAK (Alcon Inc)a

62.14 ± 3.71

BT 0.2% with BAK (Allergan Inc)a

63.61 ± 3.81

BT 0.15% without BAK (Allergan Inc)b

40.36 ± 3.17

BAK-Sb

41.02 ± 2.17

PBSc

37.57 ± 2.14

ZASd

77.21 ± 3.95

fMLPd

100.71 ± 3.94

  1. (Mean migration ± standard deviation in μm)
  2. aDrugs inducing significant chemotaxis (p < 0.01 versus PBS controls)
  3. bDrugs inducing no significant chemotactic effect (p > 0.05 versus PBS controls)
  4. cNegative control
  5. dPositive controls
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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