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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: Depressive effectiveness of vigabatrin (γ-vinyl-GABA), an antiepileptic drug, in intermediate-conductance calcium-activated potassium channels in human glioma cells

Fig. 3

Concentration-response curve for VGB-induced suppression of IKCa channels recorded in human 13–06-MG cells (mean ± SEM; n=11–14 for each point). VGB was added at various concentrations (0.3–100 μM) to the bath, and the activity of IKCa channels was detected at − 80 mV relative to the bath. The smooth curve was well fitted with a least-squares procedure to a modified Hill function

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