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Fig. 1 | BMC Pharmacology and Toxicology

Fig. 1

From: Safety of natural anthraquinone emodin: an assessment in mice

Fig. 1

Emodin is rapidly glucuronidated when given I.P. and P.O. and is more bioavailable in females. a. Chemical structure of emodin (PubChem CID: 3220). b-e. Total, glucuronidated, and free emdoin bioavailability in male and female mice 1 h, 4 h, and 12 h after given I. P at b) 20 mg/kg and c) 40 mg/kg and P.O. at d) 20 mg/kg and e) 40 mg/kg. n = 3–4/dose/timepoint/sex. * indicates statistical significance (p < 0.05) between sexes of total emodin. # indicates statistical significance (p < 0.05) between sexes of glucuronidated emodin

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