Fig. 4

The inhibition of writhings (%) recorded for ibuprofen derivatives (4a-n) in comparison with ibuprofen (the data represent the mean of 8 values ± standard deviation). One-way analysis of variance (ANOVA) followed by Tukey post hoc test was performed. & - p < 0.01 vs. vehicle, # - p < 0.001 vs. vehicle, * - p < 0.05 vs. ibuprofen, $ - p < 0.01 vs. ibuprofen